摘要
以低共熔溶剂氯化胆碱-对甲苯磺酸为催化剂,以对硝基苯甲酸和乙醇为原料,合成对硝基苯甲酸乙酯,考察了低共熔溶剂用量、反应物配比、回流时间等因素对产物收率的影响。较佳工艺条件为:氯化胆碱-对甲苯磺酸用量1.5 g,对硝基苯甲酸与乙醇摩尔比1∶6,回流时间2.0 h,此条件下对硝基苯甲酸乙酯的收率可达95%。此外,低共熔溶剂可回收和重复使用5次,酯化产物的收率没有显著下降。
The ethyl p-nitrobenzoate was synthesized with p-nitrobenzoic acid and ethanol as starting materials,choline chloride-p-toluene sulfonic acid as catalyst.The influences of deep eutectic solvent dosage,reactants ratio and reflux time on the yield of the product were discussed.The yield of ethyl p-nitrobenzoate could reach 95%,under the optimum reaction conditions with amount of choline chloride-p-toluene sulfonic acid 1.5 g,molar ratio of p-nitrobenzoic acid to ethanol 1∶6 and reflux time 2.0 h.Moreover,the deep eutectic solvent could be recovered and reused for five times,and the yield of esterification product was not decreased significantly.
作者
王英磊
李文欢
赵天舒
李默
Wang Yinglei;Li Wenhuan;Zhao Tianshu;Li Mo(School of Biological and Chemical Engineering,Nanyang Institute of Technology,Nanyang 473004,He’nan,China)
出处
《精细石油化工》
CAS
2021年第2期30-33,共4页
Speciality Petrochemicals
基金
河南省科技攻关项目(182102310601)。
