固本化痰祛瘀汤治疗慢性阻塞性肺疾病缓解期的临床疗效

The clinical effect of Guben Huatan Quyu Decoction on COPD in remission stage

目的探讨固本化痰祛瘀汤治疗慢性阻塞性肺疾病(COPD)缓解期的临床疗效。方法选取2017年4月至2020年4月宜川县中医医院与安康市人民医院收治的142例COPD缓解期患者为研究对象,依据随机数字法分为两组,对照组进行异丙托溴铵治疗,研究组进行固本化痰祛瘀汤治疗。观察分析两组患者的肺功能、NO水平、ET水平及生存质量情况。结果研究组FEV1、FVC及FEV1/FVC指标高于对照组,差异具有统计学意义(P<0.05);研究组NO水平高于对照组(P<0.05),研究组ET水平低于对照组,差异具有统计学意义(P<0.05)。结论与西医治疗相比,对COPD缓解期患者使用固本化痰祛瘀汤治疗效果显著,不仅可以有效改善患者肺功能,还可以降低其ET水平,提高NO水平,有利于进一步改善其生存质量,促进其康复。

Objective To explore the clinical efficacy of Guben Huatan Quyu Decoction in the treatment of chronic obstructive pulmonary disease(COPD)in remission stage.Methods 142 patients with COPD in remission stage admitted to Ankang people′s Hospital from April 2017 to April 2020 were selected as the study subjects,which were divided into two groups according to the random number method.The control group received treatment with ipratropium bromide,while the study group received treatment with Guben Huatan Quyu Decoction.The pulmonary function,NO level,ET level and quality of life of the two groups were observed and analyzed.Results The indexes of FEV1,FVC and FEV1/FVC in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05).NO level of the study group was higher than that of the control group(P<0.05),ET level of the study group was lower than that of the control group,the difference was statistically significant(P<0.05).Conclusion Compared with western medicine treatment,the treatment effect of Guben Huatan Quyu Decoction for COPD in remission stage is significant.It can not only effectively improve the lung function of patients,but also reduce ET level and increase NO level,which is beneficial to further improve the quality of life and promote rehabilitation.It is worth promoting vigorously.