小剂量间断右旋糖酐铁联合辅食添加指导治疗婴幼儿缺铁性贫血的疗效分析

Analysis of the therapeutic effect of low dose intermittent iron dextran combined with supplementary food on iron deficiency anemia in infants

目的:探讨小剂量间断右旋糖酐铁联合辅食添加指导治疗婴幼儿缺铁性贫血的疗效。方法:选取2019年1月—2020年1月收治的缺铁性贫血婴幼儿75例,随机分为观察组和对照组。观察组口服右旋糖酐铁口服液,每次5~10 mL,每周3次,餐间服用,同时进行辅食添加指导;对照组口服常规剂量右旋糖酐铁口服液,每日5~10 mL,分成3次,餐间服用,同时指导辅食添加。治疗8周后观察两组临床疗效及并发症。结果:两组治疗总有效率及复查的血红蛋白(Hb)、平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)比较差异无统计学意义(P>0.05)。并发症发生率以,观察组7.5%,对照组25.7%,两组比较,差异有统计学意义(P<0.05)。结论:小剂量间断右旋糖酐铁联合辅食添加指导治疗婴幼儿缺铁性贫血,并发症发生率低,治疗效果良好。

Objective:To explore the effect of low dose intermittent iron dextran combined with supplementary food in the treatment of iron deficiency anemia in infant.Methods:From January 2019 to January 2020,75 infants with iron deficiency anemia were selected,randomly divided into two groups,the treatment group was given oral dextran iron oral liquid 5~10 mL/d,three times a week,taking it between meals,and at the same time,the supplementary food was added to guide;the control group was given oral dextran iron oral liquid 5~10 mL/d,divided into three times,taking it between meals,at the same time,the supplementary food was added,after 8 weeks of treatment,the clinical efficacy and complications of the two groups were observed.Results:There was no significant difference between the two groups in the total effective rate of treatment and the blood indexes of hemoglobin(Hb),mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH)and mean corpuscular hemoglobin concentration(MCHC)(P>0.05).The incidence of complications was 7.5%in the treatment group and 25.7%in the control group.The difference was statistically significant(P<0.05).Conclusion:Low dose intermittent iron dextran combined with complementary feeding guidance in the treatment of iron deficiency anemia in infants has a low incidence of complications and good therapeutic effect.