摘要
Polymeric nanomedicine is a promising and rapidly evolving field.Among the different polymeric carriers,polymeric micelle(PM) with nanoscale size exhibit potent physical and biological advantages including excellent solubility and pharmacokinetics,enhanced efficacy and lower toxicity.PM has garnered increasing intere st in research and in the clinic.This review will highlight the clinical outcomes of several PM-based formulations,and further summarized their preparation methods,strengths and challenges.
基金
financially supported by Fundamental Research Funds for the Central Universities(No.201964018)
National Natural Science Foundation of China(No.31872754)
Qingdao Program for Original Innovation and Fundamental Research(No.18-2-2-73-jch)。
