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病毒感染对睾丸结构与功能的影响及其机制 被引量:1

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摘要 睾丸是精子发生的主要场所,已证实寨卡病毒、腮腺炎病毒、人类免疫缺陷病毒等多种病毒感染后,可造成男性感染者生育力下降,甚至不育。睾丸具有免疫豁免及固有免疫防御特性,在维持生精微环境平衡及正常的精子发生过程中具有重要作用。病毒感染可破坏睾丸免疫平衡,引发感染或睾丸炎,损害生育能力。本文从免疫学角度就病毒感染对睾丸结构与功能的影响及其机制进行综述,旨在为病毒感染者生育力改善措施的研究提供新的思路。
出处 《癌变.畸变.突变》 CAS 2021年第2期153-156,共4页 Carcinogenesis,Teratogenesis & Mutagenesis
基金 广东省自然科学基金(2019A1515010755) 广州市科技计划项目(201904010024) 广州市卫生健康科技引导项目(20191A011087)。
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  • 1Wira CR, Fahey JV, Sentman CL, Pioli PA, Shen L. Innate and adaptive immunity in female genital tract: cellular responses and interactions. Immunol Rev 2005; 206: 306-335.
  • 2Kaushic C, Ferreira VH, Kafka JK, Nazli A. HIV infection in the female genital tract: discrete influence of the local mucosal microenvironment. Am J Reprod Immuno/201O; 63: 566-575.
  • 3Brotman RM, Ravel J, Bavoil PM, Gravitt PE, Ghanem KG. Microbiome, sex hormones, and immune responses in the reproductive tract: challenges for vaccine development against sexually transmitted infections. Vaccine 2014; 32: 1543-1552.
  • 4Ferreira VH, Kafka JK, Kaushic C. Influence of common mucosal co?factors on HIV infection in the female genital tract. Am J Reprod Immunol2014; 71: 743-554.
  • 5Blaskewicz CD, Pudney J, Anderson OJ. Structure and function of intercellular junctions in human cervical and vaginal mucosal epithelia. Bioi Reprod 2011; 85: 97-104.
  • 6Anderson OJ, Marathe J, Pudney J. The structure of the human vaginal stratum corneum and its role in immune defense. Am J Reprod Immunol2014; 71: 618-623.
  • 7Wira CR, Richardson J, Prabhala R. Endocrine regulation of mucosal immunity: effect of sex hormones and cytokines on the afferent and efferent arms of the immune system in the female reproductive tract. In: Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR (ed.) Handbook of Mucosal Immunology. San Diego, CA: Academic Press, 1994: 705-718.
  • 8Wira CR, Crane-Godreau MA, Grant-Tschudy KS. Endocrine regulation of the mucosal immune system in the female reproductive tract. In: Lamm ME Mestecky J, Strober W, Bienenstock J, McGhee JR and Mayer L (ed.) Mucosal Immunology. San Diego, CA: Elsevier Academic Press, 2005: 1661-1676.
  • 9Kaushic C, Roth KL, Anipindi V, Xiu F. Increased prevalence of sexually transmitted viral infections in women: the role of female sex hormones in regulating susceptibility and immune responses. J Reprod Immunol2011; 88: 204-209.
  • 10Mestecky J, Moldoveanu Z, Russell MW. Immunologic uniqueness of the genital tract: challenge for vaccine development. Am J Reprod Immunol2005; 53: 208-214.

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