中国艾滋病患者群体中抑郁症患病率Meta分析

Meta-analysis of the prevalence of depression among Chinese HIV/AIDS patients

目的艾滋病患者抑郁症引起的并发症会给患者及其家属,甚至社会带来严重的危害,了解我国艾滋病患者抑郁症的患病率,在其抑郁症的早期进行预防和干预,可以有效降低患者的治疗费用,维护患者的身心健康。方法检索中国期刊全文数据库、万方数据资源系统、维普数据库、Pubmed、SCI、Embase和Cochrane library发表的2000年1月至2020年1月所有相关研究。使用Stata 15.0软件对纳入的文献进行Meta分析。结果Meta分析结果显示,中国艾滋病患者抑郁症合并患病率为53.8%[95%可信区间(CI):47.7%~60.0%];PHQ-9测量的抑郁症患病率最高,为70.6%;西部地区的艾滋病患者抑郁症患病率高于东北、中部和东部,为57.2%。结论中国艾滋病患者抑郁症的患病率较高,需要及时对艾滋病患者进行早期的心理干预和预防,减少抑郁症的发生。

Objective As the complications caused by depression in AIDS patients will bring serious harm to patients and their families,and even society,it is necessary to understand the prevalence of depression among AIDS patients in China,and to prevent and intervene in the early stages of depression,so as to effectively reduce the patient’s the cost of treatment to maintain their physical and mental health.Methods All relevant studies published in Chinese Journal Full-text Database,Wanfang Data Resource System,Weipu Database,Pubmed,SCI,Embase,and Cochrane Library from Jan 2000 to Jan 2020 were searched.Meta-analysis was performed on the included literature using Stata 15.0 software.Results The meta-analysis showed that the prevalence of depression in AIDS patients in China was 53.8%(95%CI:47.7%to 60.0%).The highest prevalence of depression measured by PHQ-9 was 70.6%.The prevalence of depression among AIDS patients in the western regions was 57.2%,higher than in the northeast,central and eastern regions.Conclusion The prevalence of depression among AIDS patients in China is relatively high.Early psychological intervention and prevention of AIDS patients should be carried out to reduce the incidence of depression.