成年人腹盆腔手术患者机械预防静脉血栓的最佳证据总结

Best evidence summary of mechanical prevention of venous thrombosis in adult patients undergoing abdominal and pelvic surgery

目的检索、评价和总结成年人腹盆腔手术患者机械预防静脉血栓栓塞症(VTE)的相关证据,为临床提供科学依据。方法系统检索并筛选指南网、数据库有关成年人腹盆腔手术患者机械预防VTE的证据,包括指南、证据总结、临床决策、系统评价、专家共识,检索时限为建库至2020年1月19日。由2名经过循证培训的研究人员根据文献类型选择合适的评价工具进行质量评价,并将推荐意见进行提取、翻译和整合。结果共纳入文献24篇,包括指南7篇、证据总结2篇、推荐实践1篇、系统评价12篇、专家共识2篇。从入院评估、禁忌证、适用人群、启动时机、持续时间、患者教育6个方面进行证据总结,共形成10条推荐意见。结论本研究总结了成年人腹盆腔手术患者机械预防VTE的最佳证据,为规范临床机械预防提供循证依据。

Objective To retrieve,evaluate and summarize the relevant evidence of mechanical prevention of venous thromboembolism(VTE)in adult patients undergoing abdominal and pelvic surgery,so as to provide a scientific basis for clinical practice.Methods We systematically retrieved and screened the guide network and database for evidence on mechanical prevention of VTE in adult patients undergoing abdominal and pelvic surgery,including guidelines,evidence summary,clinical decision-making,systematic review,and expert consensus.The search time limit was to build the database until January 19,2020.Two researchers who had undergone evidence-based training selected appropriate evaluation tools according to different types of literature to evaluate the quality of the literature,and to extract,translate and integrate recommendations.Results A total of 24 articles were included,including 7 guidelines,2 evidence summaries,1 recommended practice,12 systematic reviews,and 2 expert consensus.The evidence was summarized from 6 aspects,namely admission assessment,contraindications,applicable population,starting time,duration and patient education,and a total of 10 recommendations were formed.Conclusions This study summarizes the best evidence for mechanical prevention of VTE in adult patients undergoing abdominal and pelvic surgery,and provides evidence-based evidence for standardizing clinical mechanical prevention.