摘要
Long non-coding RNAs(LncRNAs)comprise different types of RNA polymerase II-transcripted molecules,exhibit nucleotide lengths of greater than 200 nucleotides and do not undergo protein translation.Due to their characteristic feature of open reading frame,they have often been labelled as the"noise"of genomic transcription.Even though lncRNAs are widely transcribed genes,their expression level is lower than that of the protein-coding genes.Depending on their position relative to the protein-coding genes in the genome,lncRNAs are categorized as sense,antisense,bidirectional,intronic,and intergenic.
基金
This research was supported by a grant from the National Natural Science Foundation of China(No.81872535)。