新型冠状病毒治疗靶点及药物研究进展

Research Progress of Therapeutic Targets and Drugs of SARS-CoV-2

目的探索SARS-CoV-2的治疗靶点,治疗药物和疫苗研发的近况,为其后期的研究提供思路。方法通过检索国内外的专业数据库,对SARS-CoV-2的最新文献进行解读,获取相关数据。结果目前研究出2个抗病毒药物靶点,一个抗体和疫苗的靶点及一个开发检测试剂的靶点,可能的有效药物和疫苗也已经开始临床研究。结论目前SARS-CoV-2的针对性靶点已清楚,候选药物和疫苗的疗效尚待确认。

OBJECTIVE To explore the targets of treatment,the therapeutic drugs and the recent development of vaccines of SARS-Co V-2,and to provide some ideas for its later research. METHODS The latest SARS-Co V-2 literatures were interpretedand relevant data were obtained by searching professional databases at home and abroad. RESULTS Two antiviral drug targets,one antibody and vaccine target,and one target for developing detection reagents have been developed in recent. The possible effective drugs and vaccines have started clinical research. CONCLUSION The targets of SARS-Co V-2 are clear now. And the clinical efficacy of candidate medicines and vaccines have yet to be confirmed.