期刊文献+

Et_(3)N-Catalyzed Cycloaddition Reactions ofα-(Trifluoromethyl)styrenes with 2,2,2-Trifluorodiazoethane to Access Bis(trifluoromethyl)-Substituted Pyrazolines

原文传递
导出
摘要 A novel and practical method for the synthesis of 3,5-bis(trifluoromethyl)-4,5-dihydro-1H-pyrazoles by [3+2] cycloaddition reactions of α-(trifluoromethyl)styrenes with 2,2,2-trifluorodiazoethane (CF3CHN2) has been developed. The cyclization reaction proceeds smoothly in the presence of a catalytic amount of Et_(3)N, affording a variety of bis(trifluoromethyl)-substituted 2-pyrazolines in good to excellent yields. This method also exhibits a broad substrate scope and tolerates various functional groups.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2021年第2期301-306,共6页 中国化学(英文版)
基金 support from the National Key Research and Development Program of China(No.2017YFD0200505)。
  • 相关文献

参考文献2

二级参考文献3

共引文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部