地佐辛超前镇痛在妇科腹腔镜手术中的应用效果分析

Analysis of the effect of dizoxine preemptive analgesia in gynecological laparoscopic surgery

目的:探讨地佐辛超前镇痛在妇科腹腔镜手术中的应用效果。方法:2019年3月-2020年3月收治行妇科腹腔镜手术治疗患者80例,随机分为两组,各40例。研究组在麻醉诱导前静脉注射地佐辛;对照组于麻醉诱导前注射同等数量的生理盐水。比较两组镇静效果、术后不良反应情况及不同时间点VAS评分。结果:研究组术后1 h、2 h、4 h、8 h VAS评分均显著低于对照组,差异有统计学意义(P<0.05);研究组不良反应发生率显著低于对照组,差异有统计学意义(P<0.05);研究组术后15 min、30 min及1 h镇静效果评分均显著高于对照组,差异有统计学意义(P<0.05)。结论:用地佐辛作为妇科腹腔镜手术前的超前镇痛药物,能有效缓解术后疼痛,具有非常强的镇痛和镇静效果,能减少不良反应的发生。

Objective:To investigate the effect of preemptive analgesia with dizoxin in gynecological laparoscopic surgery.Methods:From March 2019 to March 2020,80 patients who underwent gynecological laparoscopic surgery were selected,they were randomly divided into the two groups with 40 cases in each group.The study group was given intravenous injection of dizoxin before anesthesia induction.The control group was injected with the same amount of normal saline before anesthesia induction.The sedative effect,postoperative adverse reactions and VAS scores at different time points were compared between the two groups.Results:The VAS scores at 1 h,2 h,4 h and 8 h after operation in the study group were significantly lower than those in the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the study group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).The sedative effect scores at 15 min,30 min and 1 h after operation in the study group were significantly higher than those in the control group,the difference was statistically significant(P<0.05).Conclusion:As a preemptive analgesic before gynecological laparoscopic surgery,dizoxin can effectively relieve postoperative pain,has a very strong analgesic and sedative effect,and can reduce the occurrence of adverse reactions.