奶牛肝脏功能及其免疫调节作用的研究进展

Research Advance on Functions and Immune Regulation of Liver in Dairy Cows

肝脏是机体免疫的重要器官,在奶牛疾病发生、发展和防御过程中发挥着重要作用。肝脏免疫相关细胞通过受体分泌免疫相关活性物质发挥免疫调节作用,这些由肝脏合成和分泌的免疫相关活性物质直接参与构成免疫系统。此外,肝脏还参与构成肝-脑轴,调控血糖水平,进而调节奶牛的免疫功能。本文重点讨论了肝脏中的免疫相关细胞、肝细胞合成并分泌入血的免疫相关活性物质、肝-脑轴在奶牛疾病中的作用,以期强调肝脏健康在奶牛养殖中的巨大作用。

Liver is an important immune organ,which plays an important role in the occurrence,development and defense of dairy cattle diseases.The liver immune cells secrete immune related active substances through receptors,and the immune related active substances synthesized and secreted by the liver into the blood directly participate in the formation of the immune system.In addition,the liver is also involved in the formation of liver-brain axis,involved in the regulation of blood sugar level,and then regulated the immune function of dairy cows.Therefore,the objective of present review was to elucidate the role of liver immune related cells,the immune related active substances synthesized and secreted by the liver into the blood,and the liver-brain axis in dairy cow disease,in order to emphasize the great role of liver health in dairy cows feeding.