心脏磁共振纵向弛豫时间定量在肥厚型心肌病和扩张型心肌病中的应用价值

Value of T1 mapping techniques in patients with hypertrophic cardiomyopathy and dilated cardiomyopathy

采用磁共振纵向弛豫时间定量(T1 mapping)成像技术评价23例肥厚型心肌病(HCM)和18例扩张型心肌病(DCM)纤维化的价值,研究初始T1值与心功能指标的相关性。结果显示初始T1值在HCM组、DCM组及对照组分别为[(1318.4±44.7)、(1353.7±56.9)、(1267.0±24.3)ms,P<0.05],HCM患者、DCM患者左心室心肌初始T1值均与左室射血分数负相关(r=-0.488,P<0.05;r=-0.659,P<0.01)。研究表明T1mapping技术可以评价HCM及DCM心肌纤维化情况,HCM及DCM患者中左室心肌初始T1值所示心肌纤维化与心功能负相关。

To explore the value of T1 mapping techniques in the evaluation myocardial fibrosis in 23 patients with hypertrophic cardiomyopathy(HCM)and 18 patients with dilated cardiomyopathy(DCM),and to study the correlation between the native T1 value and cardiac function.The native T1 values in HCM group,DCM group and control group were statistical significance[(1318.4±44.7)ms,(1353.7±56.9)ms and(1267.0±24.3)ms,(P<0.05)];the native T1 value of the left ventricular myocardium in HCM and DCM patients was negatively correlated with the LVEF(r=-0.488,P<0.05;r=-0.659,P<0.01).The study showed that T1 mapping evaluated the myocardial fibrosis of HCM and DCM noninvasively.The myocardial fibrosis shown by the native T1 value of the left ventricular myocardium was negatively correlated with cardiac function in patients with HCM and DCM.