新型冠状病毒肺炎复阳患者的临床特点、预后及传染性

Clinical characteristics,prognosis,and infectiousness of COVID-19 patients with COVID-19 recurrence

目的分析总结新型冠状病毒肺炎(COVID-19)复阳患者的临床特征、预后及传染性。方法回顾性统计2020年2月10日至2020年4月15日湖北省武汉市火神山医院收治及随访的复阳患者,描述患者的基础特征、临床表现、治疗方案、疾病预后及传染性,并与非复阳患者进行比较。结果复阳患者男33例(50.8%),女32例(49.2%),中位年龄58(44,65)岁,合并基础疾病24例(36.9%),与非复阳患者比较无明显差异(P>0.05);普通型患者比例(87.7%)显著高于非复阳患者;所有复阳患者新型冠状病毒(SARS-CoV-2)核酸均转阴,未发现复阳患者周围人群感染情况。结论COVID-19复阳患者预后良好,复阳可能与患者性别、年龄、基础疾病、重型患者、淋巴细胞数无相关性;普通型患者更容易复阳。

Objective To analyze and summarize the clinical characteristics,prognosis and infectiousness of COVID-19 patients with COVID-19 recurrence(PR patients).Methods A retrospective study was performed on the RP patients admitted and followed up in Huoshenshan Hospital of Wuhan City from February 10,2020 to April 15,2020.The basic characteristics,clinical manifestations,treatment options,disease prognosis and infectiousness of the patients were collected and analyzed.Results Among all patients male RP patients accounted for 50.8%(33 cases),and femal accounted for 49.2%(32 cases),with a median age of 58(IQR,44-65)years old,36.9%(24 cases)of them accompanied with underlying diseases,which was no significant difference when compared with those of non-RP patients.87.7%of RP patients was moderate cases,which was significantly higher than that of non-RP patients.SARS-CoV-2 RNA of all RP patients eventually turned negative.No infection was found among the people around the RP patients.Conclusion All RP patients had a good prognosis,and no correlation was found between RP and gender,age,underlying diseases,severe patients,or lymphocyte count.Compared with severe patients,SARS-CoV-2 RNA of moderate patients shows higher RP rate.