康复期成年精神障碍患者参与能力对其药物依从性的影响

Does Participation Influence the Medication Adherence among Adults with Mental Disorders during their Rehabilitation?

目的了解康复期成年精神障碍患者参与能力对其药物依从性的影响。方法2019年11月至2020年1月,采用便利抽样方法选择在江苏省南京市某三级甲等精神病院专科医院就诊的195例康复期成年精神障碍患者为研究对象,采用一般资料调查表、药物依从性评定量表(medication adherence rating scale,MARS)、患者参与能力调查问卷(patient participation ability questionnaire,PPAQ)及自知力与治疗态度问卷(insight and treatment attitude questionnaire,ITAQ)对其进行调查。结果康复期成年精神障碍患者的MARS、PPAQ及ITAQ得分分别为(4.48±1.97)、(102.72±12.71)、(11.89±4.45)分。多因素线性回归分析结果显示,PPAQ、ITAQ、病程是影响患者药物依从性的独立影响因素(均P<0.05)。结论康复期成年精神障碍患者参与能力、自知力与治疗态度、病程是患者药物依从性的独立影响因素;管理者可采取针对性的策略改善患者的参与能力,提高其对疾病的自知力与治疗态度,从而提升药物依从性,降低疾病的复发率。

Objective To explore the effects of participation on medication adherence among adults with mental disorders during their rehabilitation.Methods Convenient sampling was used to select 195 adults with mental disorders during their rehabilitation who visited a tertiary psychiatric hospital in Nanjing City,Jiangsu Province from November,2019 to January,2020.The general information questionnaire,the Medication Adherence Rating Scale(MARS),the Patient Participation Ability Questionnaire(PPAQ),and the Insight and Treatment Attitude Questionnaire(ITAQ)were used for investigation.Results The MARS score,the PPAQ score and the ITAQ score were(4.48±1.97),(102.72±12.71),(11.89±4.45),respectively among adults with mental disorders dursing their rehabilitation.Multiple linear regression analysis showed that the PPAQ score,the ITAQ score and the course of disease were independent influencing factors of patients’medication adherence(all P<0.05).Conclusions Participation ability,insight and treatment attitude,and the course of disease are independent influencing factors of medication adherence among adults with mental disorders dursing their rehabilitation.Managers can take targeted strategies to improve patients’participation ability,and promote their insight and treatment attitude to disease,so as to enhance their medication adherence and reduce the recurrence rate of disease.