淋巴细胞亚群检测在结核病诊疗中的应用进展

The research progress of lymphocyte subsets detection in diagnosis and treatment of tuberculosis

结核病是由结核分枝杆菌感染引起的慢性传染性疾病。当结核分枝杆菌侵入机体的菌量和毒力大于机体免疫系统的防御能力时,就会发病;免疫功能低下者更易感染发病。目前淋巴细胞亚群检测成为临床分析结核病患者免疫状况的手段之一,但其诊疗意义尚没有统一的认识。作者通过概述结核病患者外周血中淋巴细胞亚群百分比及绝对计数在结核病诊断和治疗中的应用研究进展,以判断其临床价值,为结核病患者的免疫诊断和免疫治疗提供依据。

Tuberculosis is a chronic infectious disease caused by M.tuberculosis.When the amount and virulence of M.tuberculosis invading the body are greater than the defense ability of the immune system,the tuberculosis will occur.Those with low immune function are more susceptible to be infected.At present,lymphocyte subsets detection has become one of the methods to analyze the immune status of tuberculosis patients,but its significance in the diagnosis and treatment of tuberculosis has not been recognized.This paper summarized the application progress of lymphocyte subsets percentage and absolute count in the peripheral blood of tuberculosis patients in diagnosis and treatment of tuberculosis,so as to judge its clinical value and provide the basis for immunodiagnosis and immunotherapy of tuberculosis patients.