细菌胞外多糖生物合成转录调控因子研究进展

Advances in transcription regulators of bacterial exopolysaccharides biosynthesis

细菌胞外多糖(Exopolysaccharide,EPS)因其独特的理化特性和生理活性,在食品、制药和化工等领域广泛应用。在食品行业中,黄原胶、结冷胶和热凝胶等细菌EPS备受青睐。转录调控因子能在转录水平上调控eps基因的表达,影响细菌EPS的生物合成。目前细菌EPS转录调控因子的研究报道较少,且多数已知的EPS转录因子调控机制尚未阐明。本文总结了近年来细菌EPS调控因子的研究进展,重点介绍其研究方法和调控机制,以期为细菌EPS转录调控研究提供借鉴。

Bacterial exopolysaccharides(EPS)are widely used in food,pharmaceutical,and chemical fields due to their unique physicochemical properties and physiological activities.Bacterial EPS such as xanthan gum,gellan gum,and thermal gel are widely applied and favored in food industry.Transcriptional regulators can regulate the expression of eps genes at transcription level to affect bacterial EPS biosynthesis.Moreover,the regulatory mechanism of most reported EPS transcriptional regulators has not been elucidated.This review summarizes the progress of bacterial EPS transcriptional regulators in recent years and focuses on the research methods and regulatory mechanisms,in order to provide reference for transcription regulation research of bacterial EPS.