梅毒血清固定最新研究进展

New Progress in Syphilis Serofast

梅毒血清固定是患者抗梅毒治疗后非梅毒螺旋体血清学试验在规定的随访时间内持续阳性的一种特殊血清学现象。梅毒血清固定在临床常见但其机制迄今不明。多数研究认为这种现象的发生可能与机体的免疫失衡相关。深入研究梅毒血清固定发生的相关因素及其发病机制将有助于临床医生判断患者预后,避免过度治疗和治疗不足,具有十分重要的临床意义。

Syphilis serofast is a serological phenomenon in which non-treponema pallidum serological test is continuously positive within the follow-up period after anti syphilis treatment. Syphilis serofast is common, however its pathogenesis is still unknown. Most people believe that this serological phenomenon may be related to unbalance of immune response. Understanding the pathogenesis of syphilis serofast can help clinicians to avoid over treatment and/or insufficient treatment of the patients,which has important clinical significance.