三维能量多普勒超声评估颈动脉斑块与缺血性卒中发生的相关性

Correlation Between Carotid Plaque and Ischemic Stroke Evaluated by Three-Dimensional Power Doppler Imaging

目的探讨三维能量多普勒成像(3D-PDI)评估颈动脉斑块与缺血性卒中发生的相关性。资料方法回顾性分析142例常规超声检查发现的颈动脉斑块患者,采用3D-PDI检查并记录斑块的血管指数(VI)、血流指数(FI)、血管血流指数(VFI)。根据头颅CT结果,分为脑梗死组67例和非脑梗死组75例。采用Logistic回归分析颈动脉斑块与脑梗死发生的相关性。结果梗死组的VI、FI、VFI均高于非脑梗死组(VI:0.72±0.23比0.48±0.18;FI:23.41±11.25比13.80±9.14;VFI:33.76±9.45比25.22±6.13;均P<0.01)。Logistic回归分析显示,低回声斑块(OR=2.42)、不规则斑块(OR=1.92)、溃疡斑块(OR=4.21)均为缺血性卒中发生的相关因素(P均<0.05)。VI(OR=4.01)、FI(OR=4.35)、VFI(OR=4.57)也是缺血性卒中发生的相关因素(P均<0.05)。结论颈动脉斑块低回声、形态不规则、溃疡斑块及VI、FI、VFI升高与缺血性卒中的发生具有相关性。

Purpose To investigate the correlation between carotid plaque and ischemic stroke by three-dimensional power Doppler imaging(3D-PDI).Materials and Methods 142 patients with carotid artery plaque observed by conventional ultrasound were retrospectively analyzed.Vascularization index(VI),flow index(FI)and vascularization-flow index(VFI)of plaque were examined by 3D-PDI and recorded.According to CT results of the head,67 patients were divided into cerebral infarction group and 75 non-cerebral infarction group.Logistic regression was used to analyze the correlation between carotid plaque and cerebral infarction.Results The values of VI,FI and VFI of the cerebral infarction group were higher than those of the non-cerebral infarction group(VI:0.72 e ce vs.0.48±0.18;FI:23.41±0.18e vs.13.80±9.14;VFI:33.76±9.1 vs.25.22±6.13;P<0.01).Logistic regression analysis showed that hypoechoic plaque(OR=2.42),irregular plaque(OR=1.92)and ulcer plaque(OR=4.21)were risk factors of ischemic stroke(P<0.05).VI(OR=4.01),FI(OR=4.35),VFI(OR=4.57)were also risk factors of ischemic stroke(P<0.05).Conclusion The hypoechoic,irregular shape of carotid plaque,ulcer plaque and the increase of VI,FI and VFI are related to the occurrence of ischemic stroke.