木瓣树枝叶甲醇提取物的化学成分

Chemical constituents of methanol extracts from branches and leaves of Xylopia vielana

木瓣树(Xylopia vielana Pierre)为木瓣树属(Xylopia Linn.)高大乔木,分布于热带和亚热带地区[1]。在中国民间,木瓣树树皮可用于制作通经剂,叶可用于治疗风湿病和疼痛;在越南南部,木瓣树还可用于治疗疟疾[2]。从木瓣树根及叶中已发现64个化合物,包括倍半萜二聚体类、生物碱类及苯环衍生物,其中,倍半萜二聚体类及生物碱类化合物具有一定的抗炎和抗肿瘤活性[3-4]。为深入了解木瓣树化学成分,丰富该属植物化合物库,本研究首次对木瓣树枝叶进行了化学成分分离和鉴定,以期为该植物后续活性研究提供物质基础。

Nine compounds were isolated and identified from methanol extracts of branches and leaves of Xylopia vielana Pierre.They are N-trans-feruloyltyramine(1),N-cis-feruloyltyramine(2),1,2-dihydro-6,8-dimethoxy-7-hydroxy-1-(3,5-dimethoxy-4-hydroxyphenyl)-N1,N2-bis-[2-(4-hydroxyphenyl)ethyl]-2,3-naphthalene dicarboxamide(3),methyl 2,4-dihydroxy-3,6-dimethylbenzoate(4),methyl 3,4-dihydroxybenzoate(5),(Z)-7-octadecen-9-ynoic acid methyl ester(6),(-)-epi-syringaresinol(7),(-)-syringaresinol(8),and 2,4-dichlorophenyl 2,4-dichlorobenzoate(9).All the above compounds are isolated from this plant for the first time.