胃镜检查对^(13)C和^(14)C尿素呼气试验结果影响的回顾性分析

A retrospective study of different effects of ^(13)C or ^(14)C urea breath test before and after gastroscopy

目的分析胃镜检查前后对13C和14C尿素呼气试验结果的影响。方法回顾性分析广东省第二中医院2019年9月至2020年1月行13C或14C尿素呼气试验并行普通胃镜检查的受检者379例,比较胃镜检查前后行13C或14C尿素呼气试验阳性率的差异。结果13C尿素呼气试验在胃镜检查前阳性率为31.08%,在胃镜检查后阳性率为31.51%,两者间比较,差异无统计学意义(P>0.05);14C尿素呼气试验在胃镜检查前阳性率为42.00%,在胃镜检查后阳性率为24.14%,两者间比较,差异有统计学意义(P<0.05)。结论胃镜检查会影响14C尿素呼气试验的检测结果,但不会影响13C尿素呼气试验的检测结果。因此,在胃镜检查后若要行呼气试验,建议优先选择13C尿素呼气试验;若要选择14C尿素呼气试验,建议在胃镜检查前完成。

Objective To analysis the different effects of 13C or 14C urea breath test before and after gastroscopy.Methods A retrospective study of 379 patients in Guangdong Second Traditional Chinese Medicine Hospital from Sep.2019 to Jan.2020 who took the 13C or 14C urea breath test and gastroscopy.The positive rate of 13C or 14C urea breath test before and after gastroscopy was compared.Results The positive rate of Helicobacter pylori(H.pylori)of 13C urea breath test was 31.08%before gastroscopy and 31.51%after gastroscopy,there was no significant difference(P>0.05).And the positive rate of H.pylori of 14C urea breath test was 42.00%before gastroscopy and 24.14%after gastroscopy,there was significant difference(P<0.05).Conclusion Gastroscopy does affect the results of 14C urea breath test for detection of H.pylori infection but not 13C urea breath test.So the 13C urea breath test is better if one want to take the urea breath test after gastroscopy.It is better if one take 14C urea breath test before gastroscopy.