布托啡诺、地佐辛联合芬太尼用于腹腔镜术后PCIA效果观察

Observation of the effect of butorphanol or dezocine combined with fentanyl on PCIA after laparoscopic surgery

目的:比较布托啡诺、地佐辛联合芬太尼用于术后患者静脉自控镇痛(PCIA)的效果。方法:选择150例腹腔镜术后患者按入院时间分为芬太尼组(S组)、布托啡诺联合芬太尼组(BS组)、地佐辛联合芬太尼(DS组)各50例。比较三组PCIA的使用情况、不良反应及镇痛、镇静效果。结果:DS组有效和实际按压PCIA泵次数、PCIA泵药物减少量、曲马多用量、不良反应发生率均少于BS和S组(P<0.05);术后1~2 h BS组NRS和Ramsay评分优于DS和S组(P<0.05),而术后6~48 h DS组NRS和Ramsay评分优于BS组、S组(P<0.05)。结论:地佐辛联合芬太尼用于腹腔镜后PCIA镇痛、镇静效果最佳。

Objective:To compare the effects of butorphanol or dezocine combined with fentanyl for patient-controlled intravenous analgesia(PCIA)in postoperative patients.Methods:One hundred and fifty patients who underwent laparoscopic surgery were selected and divided into a fentanyl group(S group),a butorphanol combined with fentanyl group(BS group)and a dezocine combined with fentanyl(DS group)with 50 cases each based on their admission time.The usage of PCIA,the incidence of adverse reactions and the analgesia and sedation were compared among the three groups.Results:The times of effective and actual compressions of the PCIA pump,the drug reduction in the PCIA pump,the tramadol dosage and the incidence of adverse reactions were less in the DS group than the BS and S groups(P<0.05).NRS and Ramsay scores at 1 to 2 hours after surgery were better in BS group than DS and S groups(P<0.05)and NRS and Ramsay scores at 6 to 48 hours after operation were better in DS group than BS and S groups(P<0.05).Conclusion:Dezocine combined with fentanyl used after laparoscopy has the best analgesia and sedation effect.