中医适宜技术治疗经尿道前列腺切除术后下尿路症候群疗效及对患者排尿功能的影响

Curative effect of appropriate TCM technology on lower urinary tract symptoms after transurethral resection of the prostate and its influences on urination function

目的:探讨中医适宜技术治疗经尿道前列腺切除术(TURP)后下尿路症候群的疗效及对患者排尿功能的影响。方法:采用信封法将行TURP患者108例分为研究组(n=55)和对照组(n=53),对照组采用西医治疗,研究组在此基础上给予中医适宜技术治疗,比较两种治疗方式疗效,并分析对患者中医证候、排尿功能的影响。结果:两组疗效比较差异有统计学意义(94.55%与78.18%,P<0.05);治疗后研究组尿频、尿急、尿痛症状积分均显著低于对照组(P<0.05);治疗后两组最大膀胱容量(MCC)、残余尿量(PRV)、最大尿流速(Qmax)、最大逼尿肌压(Pdet)均显著升高,且研究组以上指标均明显高于对照组(P<0.05);治疗后两组前列腺素E 2(PGE 2)、β-内啡肽(β-EP)均显著升高,前列腺素F 2α(PGF 2α)降低,且研究组PGE 2、β-EP高于对照组,PGF 2α低于对照组(P<0.05);治疗后两组前列腺症状评分(IPSS)及膀胱过度活动症状评分(OABSS)均显著降低,且研究组以上评分均明显低于对照组(P<0.05)。结论:中医适宜技术在经尿道前列腺切除患者中应用较佳,可显著改善患者术后下尿路症候群、前列腺增生及排尿功能,减轻膀胱过度活动。

Objective:To explore the curative effect of appropriate TCM technology on lower urinary tract symptoms(LUTS)after transurethral resection of the prostate(TURP)and its influences on urination function.Methods:A total of 108 patients who underwent TURP were divided into study group(n=55)and control group(n=53)by envelop method.The control group was treated with western medicine,while study group was given appropriate TCM technology on this basis.The curative effect of the two treatment methods was compared.And their influences on TCM symptoms and urination function were analyzed.Results:There was significant difference in curative effect between the two groups(94.55%vs78.18%,P<0.05).After treatment,scores of frequent urination,urgent urination and dysuria in study group were significantly lower than those in control group(P<0.05).After treatment,maximum cystometric capacity(MCC),postvoid residual volume(PRV),maximum flow rate(Qmax)maximum detrusor pressure(Pdet)in both groups were significantly increased,which were significantly higher in study group than control group(P<0.05).After treatment,prostaglandin E 2(PGE 2)andβ-endorphin(β-EP)in both groups were significantly increased,while prostaglandin F 2α(PGF 2α)was decreased.PGE 2 andβ-EP in study group were higher than those in control group,while PGF 2αwas lower than that in control group(P<0.05).After treatment,international prostate symptom score(IPSS)and Overactive Bladder Symptom Score(OABSS)in both groups were significantly decreased,which were significantly lower in study group than control group(P<0.05).Conclusion:The application of appropriate TCM technology is good in TURP patients,which can significantly improve postoperative LUTS,prostatic hyperplasia and urination function,reduce overactive bladder.