期刊文献+

丁丙诺啡透皮贴剂治疗骨科中重度慢性疼痛的效果

The Effect of Buprenorphine Transdermal Patch in the Treatment of Moderate to Severe Chronic Pain in Orthopedics
下载PDF
导出
摘要 目的对骨科中重度慢性疼痛患者采用丁丙诺啡透皮贴剂治疗的效果进行探究。方法选择2018年12月—2019年12月该院收治的骨科中重度疼痛患者86例作为该次研究对象,按照随机数表法将其划分为甲组和乙组,每组43例。采用常规治疗方法对甲组进行治疗,采用丁丙诺啡透皮贴剂对乙组进行治疗。对比两组患者的镇痛效果。结果治疗1个月后,乙组的疼痛评分(3.6±0.4)分明显低于甲组(4.9±0.7)分,两组比较差异有统计学意义(t=10.574,P<0.05);在不良反应率方面,甲组达到了30.2%,乙组达到了7.0%。乙组的不良反应率明显低于甲组,两组比较差异有统计学意义(χ^(2)=7.679,P<0.05)。结论针对骨科中重度慢性疼痛患者采用丁丙诺啡透皮贴剂治疗具有十分显著的效果,可以有效缓解患者的疼痛,而且不良反应少,具有很高的安全性。 Objective To explore the effect of buprenorphine transdermal patch treatment in orthopedic patients with moderate to severe chronic pain.Methods From December 2018 to December 2019,86 patients with moderate to severe pain in the department of orthopedics admitted to the hospital were selected as the research objects in this study,and they were divided into group A and group B according to the random number table method,each group had 43 patients.Conventional treatment methods were used to treat group A,and buprenorphine transdermal patch was used to treat group B.Compared the analgesic effects of the two groups of patients.Results After 1 month of treatment,the pain score of group B(3.6±0.4)points was significantly lower than that of group A(4.9±0.7)points.The difference between the two groups was statistically significant(t=10.574,P<0.05);in terms of adverse reaction rate,group A reached 30.2%and group B reached 7.0%.The adverse reaction rate of group B was significantly lower than that of group A,and the difference between the two groups was statistically significant(χ^(2)=7.679,P<0.05).Conclusion The use of transdermal buprenorphine patch for orthopedic patients with moderate to severe chronic pain has a very significant effect,which can effectively relieve the pain of patients,and has few adverse reactions and high safety.
作者 马利萍 MA Li-ping(Department of Pain,Liangshan County People's Hospital,Liangshan,Shandong Province,272600 China)
出处 《系统医学》 2021年第4期52-54,共3页 Systems Medicine
关键词 骨科 中重度慢性疼痛 丁丙诺啡透皮贴剂 疗效 疼痛评分 不良反应 Orthopedics Moderate to severe chronic pain Transdermal buprenorphine patch Curative effect Pain score Adverse reactions
  • 相关文献

参考文献12

二级参考文献64

  • 1田悦,郭善斌,赵平.80岁以上患者进行硬膜外镇痛的有效性和安全性[J].中国老年学杂志,2014,34(11):3028-3029. 被引量:5
  • 2Turk DC, Wilson HD, Cabana A. Treatment of chronic non-canc- er pain[J]. Lancet, 2011, 377(9784): 2226-2235. DOI: 10. 1016/S0140-6736 ( 11 ) 60402-9.
  • 3Kurita GP, Sjogren P, Juel K, et al. The burden of chronic pain : a cross-sectional survey focussing on diseases, immigration, and opioid use[J]. Pain, 2012, 153 (12) : 2332-2338. DOI: 10. 1016/j. pain. 2012.07. 023.
  • 4Hauser W, Schmutzer G, Hilbert A, et al. Prevalence of Chronic Disabling Noncancer Pain and Associated Demographic and Medi- cal Variables: A Cross-Sectional Survey in the General German Population[ J]. Clin J Pain,2015,31 (10) :886-892. DOI: 10. 1097/AJP. 0000000000000173.
  • 5Achterberg WP, Gambassi G, Finne-Soveri H, et al. Pain in Eu- ropean long-term care facilities: cross-national study in Finland, Italy and The Netherlands [ J ]. Pain, 2010, 148 ( 1 ) : 70-74. DOI: 10. 1016/j. pain. 2009.10. 008.
  • 6Gianni W, Ceci M, Bustacchini S, et al. Opioids for the treatment of chronic non-cancer pain in older people [ J ]. Drugs Aging, 2009, 26 Suppl 1:63-73. DOI: 10. 2165/11534670-000000000- 00000.
  • 7Chu MC, Law RK, Cheung LC, et al. Pain management pro- gramme for Chinese patients: a lO-year outcome review. Hang Kong Med J, 2015, 21 (4) : 304-309. DOI: 10. 12809/hk- mj144350.
  • 8Lalonde L, Choinire M, Martin E,et al. Priority interventions to improve the management of chronic non-cancer pain in primary care: a participatory research of the ACCORD program[ J]. J Pain Res, 2015, 8 : 203-215. DOI: 10. 2147/JPR. $78177.
  • 9Heimer R, Dasgupta N, Irwin KS, et al. Chronic pain, addiction severity, and misuse of opioids in Cumberland County, Maine [J]. Addict Behav, 2012, 37(3) : 346-349. DOI: 10. 1016/j. addbeh. 2011.11. 017.
  • 10Guzmm J, Esmail R, Karjalainen K, et al. Muhidisciplinary bio- psycho-social rehabilitation for chronic low back pain [ J ]. Co- chrane Database Syst Rev, 2002, ( 1 ) : CIX100963. DOI: 10. 1002/14651858. CD000963.

共引文献33

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部