丁丙诺啡透皮贴剂治疗骨科中重度慢性疼痛的效果

The Effect of Buprenorphine Transdermal Patch in the Treatment of Moderate to Severe Chronic Pain in Orthopedics

目的对骨科中重度慢性疼痛患者采用丁丙诺啡透皮贴剂治疗的效果进行探究。方法选择2018年12月—2019年12月该院收治的骨科中重度疼痛患者86例作为该次研究对象,按照随机数表法将其划分为甲组和乙组,每组43例。采用常规治疗方法对甲组进行治疗,采用丁丙诺啡透皮贴剂对乙组进行治疗。对比两组患者的镇痛效果。结果治疗1个月后,乙组的疼痛评分(3.6±0.4)分明显低于甲组(4.9±0.7)分,两组比较差异有统计学意义(t=10.574,P<0.05);在不良反应率方面,甲组达到了30.2%,乙组达到了7.0%。乙组的不良反应率明显低于甲组,两组比较差异有统计学意义(χ^(2)=7.679,P<0.05)。结论针对骨科中重度慢性疼痛患者采用丁丙诺啡透皮贴剂治疗具有十分显著的效果,可以有效缓解患者的疼痛,而且不良反应少,具有很高的安全性。

Objective To explore the effect of buprenorphine transdermal patch treatment in orthopedic patients with moderate to severe chronic pain.Methods From December 2018 to December 2019,86 patients with moderate to severe pain in the department of orthopedics admitted to the hospital were selected as the research objects in this study,and they were divided into group A and group B according to the random number table method,each group had 43 patients.Conventional treatment methods were used to treat group A,and buprenorphine transdermal patch was used to treat group B.Compared the analgesic effects of the two groups of patients.Results After 1 month of treatment,the pain score of group B(3.6±0.4)points was significantly lower than that of group A(4.9±0.7)points.The difference between the two groups was statistically significant(t=10.574,P<0.05);in terms of adverse reaction rate,group A reached 30.2%and group B reached 7.0%.The adverse reaction rate of group B was significantly lower than that of group A,and the difference between the two groups was statistically significant(χ^(2)=7.679,P<0.05).Conclusion The use of transdermal buprenorphine patch for orthopedic patients with moderate to severe chronic pain has a very significant effect,which can effectively relieve the pain of patients,and has few adverse reactions and high safety.