名老中医治疗中风病用药规律分析

Analysis on medication rules in treatment of stroke by famous traditional Chinese medicine physician

[目的]探讨分析张伯礼教授治疗中风病方剂的用药规律。[方法]对351首治疗中风的方剂进行药物名称标准化,通过频数统计、关联规则、聚类分析等数据挖掘的方法进行分析。[结果]张教授治疗中风病中用药频次由高到低的前5味药物依次为丹参、郁金、天麻、桑枝和夏枯草;所选药物以寒、平、温,苦、甘、辛的四气五味为主;归经尤其以肝经为突出,同时注重调整心经、脾经、胃经和肾经;治疗方法擅长活血化瘀、祛风湿热,发散风热、清热泻火,同时兼顾补虚(补阴、补阳、补血及补气)、平抑肝阳、息风止痉、清热燥湿。[结论]张教授治疗中风时根据患者的具体临床症状,主要从痰、瘀、虚论治,重视痰、瘀、虚的对症治疗。

[Objective]To explore and analyze the rule of Professor ZHANG Boli’s prescription for treating stroke diseases.[Methods]The drug names in 351 prescriptions for treating stroke were standardized,and the prescriptions were analyzed by data mining methods such as frequency statistics,association rules,and cluster analysis.[Results]In the treatment of stroke,the top five high-frequency drugs used by Professor Zhang was Salviae Miltiorrhizae Radix,Curcumae Radix,Gastrodiae Rhizoma,Mori Ramulus and Prunellae Spica in descending order.The selected drugs were cold,flat and warm in the nature,while were bitter,sweet,and spice in flavor.The drugs used were mainly based on the Liver Meridian.At the same time,the spleen,stomach,kidney,and lungs are balanced.In treatment,the method used is good at promoting blood circulation and removing blood stasis,dispelling wind dampness and heat,clearing heat and purging fire,while taking tonicity into account(tonifying yin,yang,blood and qi),calming liver yang,relieving wind and stopping spasm,clearing away heat and dampness.[Conclusion]Professor Zhang’s treatment of stroke is based on phlegm,stasis and deficiency according to the specific clinical symptoms of the patients,while attention is paid to the treatment of sputum and stasis.