探讨青春期多囊卵巢综合征的临床特征与治疗要点

To Explore the Clinical Characteristics and Treatment of Adolescent Polycystic Ovary Syndrome

目的探讨青春期多囊卵巢综合征的临床特征、内分泌代谢特征及治疗方案。方法在我院2019年1月-2020年1月收治的青春期多囊卵巢综合征患者中,以随机采样的原则,截取80例资料完备的作为研究对象,并将其分为40例每组,分别命名为对照组和观察组。对该种疾病的临床特征、内分泌代谢特征等资料进行分析。对照组采取雌激素治疗,观察组采取雌激素联合二甲双胍治疗。评估两组患者的治疗效果,并对其数据进行比较。结果从两组患者的治疗总有效率上比较,观察组高于对照组,差异显著(P <0.05);在治疗前后,两组患者的内分泌指标均有所改善,且观察组改善幅度高于对照组,差异具有统计学意义(P <0.05)。结论青春期多囊卵巢综合征存在内分泌紊乱的现象,且临床症状较为典型,以雌激素联合二甲双胍加以治疗,疗效显著,值得临床应用。

Objective To investigate the clinical characteristics,endocrine and metabolic characteristics and treatment of adolescent polycystic ovary syndrome.Methods A total of 80 adolescent patients with polycystic ovary syndrome admitted to our hospital from January 2019 to January 2020 were randomly sampled and divided into 40 patients per group,which were respectively named control group and observation group.The clinical characteristics,endocrine and metabolic characteristics of this disease were analyzed.The control group was treated with estrogen,and the observation group was treated with estrogen combined with metformin.The treatment outcomes of the two groups were evaluated and the data were compared.Results The total effective rate of observation group was higher than control group,the difference was significant(P<0.05).Before and after treatment,endocrine indexes in two groups were improved,and the improvement in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).Conclusion Adadolescent polycystic ovary syndrome has endocrine disorder phenomenon,and the clinical symptoms are more typical,estrogen combined with metformin treatment,the effect is significant,worthy of clinical application.