气管扩张患者采用乙酰半胱氨酸片联合阿奇霉素治疗的效果分析

Analysis of the Effect of Acetylcysteine Tablets Combined with Azithromycin in treatment of patients with Trachedilation

目的探究乙酰半胱氨酸片联合阿奇霉素用于治疗气管扩张患者的效果。方法随机选取该院自2018年12月-2020年2月期间收治的92例气管扩张患者,采取抽签法随机分为试验组(n=46)与参照组(n=46),参照组患者实施乙酰半胱氨酸片治疗,试验组患者在参照组基础上联合阿奇霉素,对比两组患者肺功能指标及治疗效果。结果试验组患者FEV1为(1.96±1.36)L高于参照组的(1.14±1.32)L,差异有统计学意义(t=2.934,P=0.004),PEF为(4.62±0.28)L/s高于参照组的(3.75±0.26)L/s,差异有统计学意义(t=15.443,P<0.05),FVC为(59.82±13.19)%高于参照组的(51.49±11.85)%,差异有统计学意义(t=3.186,P=0.002),治疗总有效率为97.83%高于参照组的80.43%,差异有统计学意义(χ^(2)=7.180,P=0.007)。结论乙酰半胱氨酸片联合阿奇霉素治疗气管扩张患者疗效显著,能有效改善肺功能指标。

Objective To explore the effect of acetylcysteine tablets combined with azithromycin in the treatment of patients with tracheal dilatation.Methods Random select 92 patients with tracheal dilatation admitted to the hospital from December2018 to February 2020 were randomly divided into experimental group(n=46)and reference group(n=46)by lottery.Patients in the reference group received acetylation In the treatment of cysteine tablets,patients in the experimental group were combined with azithromycin on the basis of the reference group,and the lung function indexes and treatment effects of the two groups were compared.Results The FEV1 of the experimental group was(1.96±1.36)L higher than that of the reference group(1.14±1.32)L,and the difference was statistically significant(t=2.934,P=0.004),and the PEF was(4.62±0.28)L/s higher than that of the reference group(3.75±0.26)L/s,and the difference was statistically significant(t=15.443,P<0.05),FVC was(59.82±13.19)%higher than(51.49±11.85)%,and the difference was statistically significant(t=3.1862,P=0.002)in the reference group,the total effective rate of treatment was 97.83%higher than 80.43%of the reference group,and the difference was statistically significant(χ^(2)=7.180,P=0.007).Conclusion Acetylcysteine tablets combined with azithromycin have a significant effect on patients with trachedilation,can effectively improve lung function indicators.