观察利舒康胶囊治疗非痴呆性血管性认知功能障碍(VCIND)的临床疗效

The Clinical Effect of Lishukang Capsules on Non-dementia Vascular Cognitive Dysfunction

目的:观察利舒康胶囊治疗非痴呆性血管性认知功能障碍(VCIND)的临床疗效。方法:选取某院2018年5月~2019年5月期间收治的70例VCIND患者作为研究对象,根据患者入院的奇偶顺序分为观察组与对照组各35例。对照组使用常规治疗,观察组在对照组的基础上使用利舒康胶囊治疗,观察两组的临床疗效、VCIND患者治疗前后的精神状态(MMSE)评分、认知功能(MoCA)评分以及血清超氧化物歧酶(SOD)值水平变化。结果:治疗后,观察组治疗有效率(91.43%)高于对照组(71.43%)(P<0.05);两组患者治疗前的MMSE评分、MoCA评分、SOD值水平比较无统计学意义(P>0.05);治疗后,观察组患者的MMSE评分、MoCA评分、SOD值均高于对照组(P<0.05)。结论:利舒康胶囊治疗可有效改善患者精神状态与认知功能,并且具有较好的治疗效果。

Objective:To observe the clinical efficacy of Lishukang capsules in treating non-dementia vascular cognitive dysfunction(VCIND).Methods:Seventy VCIND patients admitted to a hospital from May 2018 to May 2019 were selected as the research objects and divided into observation group and control group according to the order of the patients'admission,with 35 cases in each group.The control group was treated with conventional treatment,and the observation group was treated with Lishukang capsules on the basis of the control group.The clinical efficacy,mental status(MMSE)score,cognitive function(MoCA)score,and change of serum superoxide dismutase(SOD)level of VCIND patients before and after treatment were observed.Results:After treatment,the effective rate of treatment in the observation group(91.43%)was higher than that in the control group(71.43%)(P<0.05).There was no statistically significant difference in MMSE score,MoCA score and SOD value between the two groups before treatment(P>0.05).After treatment,patients in the observation group had higher MMSE scores,MoCA scores,and SOD values than those in the control group(P<0.05).Conclusion:Lishukang capsule treatment can effectively improve the mental state and cognitive function of patients,and has a good therapeutic effect.