β受体阻滞剂治疗对慢性心力衰竭患者的影响研究

Effects of Beta Blocker Therapy on Patients with Chronic Heart Failure

目的:分析β受体阻滞剂治疗对慢性心力衰竭患者的影响。方法:选取2019年1月~2020年3月某院收治的慢性心力衰竭患者126例,根据患者治疗方案的不同分为研究组(采用β受体阻滞剂治疗)与对照组(采用血管紧张素Ⅱ受体拮抗剂治疗)各63例,比较两组临床疗效、治疗前后心功能指标以及B型脑钠肽(BNP)的变化。结果:研究组总治疗有效率明显高于对照组(P<0.05);两组治疗前CI、LVEF与BNP的比较差异无统计学意义(P>0.05),研究组治疗后CI、LVEF明显高于对照组(P<0.05),且治疗后BNP明显低于对照组患者(P<0.05)。结论:β受体阻滞剂在慢性心力衰竭中的应用有助于改善患者的心功能状况,有助于提高患者的临床疗效。

Objective:To analyze the effect ofβ-blocker therapy on chronic heart failure.Methods:126 cases of patients with chronic heart failure in a hospital from January 2019 to March 2020 were selected and divided into treatment group(treated with beta blockers,63 cases)and control group(treated with angiotensinⅡreceptor antagonist,63 cases)according to the treatment methods.The changes of clinical efficacy,cardiac function and B-type brain natriuretic peptide(BNP)before and after treatment were compared between the two groups.Results:The total effective rate in the treatment group was significantly higher than that in the control group(P<0.05).There was no statistically significant difference between the two groups in CI,LVEF and BNP before treatment(P>0.05).The CI and LVEF of the treatment group were significantly higher than those of the control group(P<0.05),and BNP was significantly lower than that of the control group(P<0.05).Conclusion:The application of beta blockers in chronic heart failure is helpful to improve the cardiac function and clinical efficacy.