摘要
白花蛇舌草具有清热解毒、活血止痛、利尿消肿的作用,主要用于临床上肿瘤的辅助治疗。肿瘤的发生通常伴随着信号通路的改变,白花蛇舌草可诱导信号通路改变以发挥抗癌作用。该文对近几年基于干预细胞通路对白花蛇舌草抗癌作用机制的研究情况加以综述,为该药材的进一步深入研究和临床应用提供参考。
Baihuasheshecao(Hedyotis diffusa)has the effects of clearing heat and detoxifying,diuretic and detumescence,promoting blood circulation and relieving pain.It is mainly used as adjuvant therapy for many kinds of tumors in clinic.This paper reviews the research on the anti-cancer mechanism of hedyotis diffusa based on the intervention cell pathway in recent years.It provides a reference for further research and clinical application of this herb.
作者
王淑
孙萍
曹广尚
王信
李娜
魏永利
郭功玲
马传江
杨培民
WANG Shu;SUN Ping;CAO Guangshang;WANG Xin;LI Na;WEI Yongli;GUO Gongling;MA Chuanjiang;YANG Peimin(Shandong University of Traditional Chinese Medicine,Jinan 250355,Shandong,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011,Shandong,China)
出处
《辽宁中医药大学学报》
CAS
2021年第1期54-57,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家自然科学基金(81773950,81274052)
山东省自然科学基金(ZR2015HL116)
山东省中医药科技发展计划(2017-083)。
关键词
白花蛇舌草
信号通路
细胞凋亡
抗癌
Baihuasheshecao(Hedyotis diffusa)
signal pathway
apoptosis
anti-cancer effect mechanism
