健脾益气法治疗脾气虚弱型慢性肾小球肾炎临床研究

Research on the Significance of Invigorating Spleen and Qi in Patients with Chronic Glomerulonephritis of Deficiency of Spleen Qi

目的探讨对脾气虚弱型慢性肾小球肾炎患者采取健脾益气法治疗的意义。方法选取2018年10月—2020年1月在沈阳市骨科医院承基医院就诊的100例慢性肾小球肾炎患者,经中医辨证分型为脾气虚弱型,随机分为试验组和对照组,对照组50例采取常规治疗,试验组50例在对照组的基础上使用健脾益气法进行治疗,比较2组患者的肾功能和中医证候评分。结果试验组BUN、24 h尿蛋白定量、Scr均优于对照组患者,差异有统计学意义(P<0.05);试验组疲倦乏力、浮肿、食少纳呆、胃脘胀满、大便溏薄等积分均低于对照组,差异有统计学意义(P<0.05)。结论对脾气虚弱型慢性肾小球肾炎患者采取健脾益气法进行治疗,可以有效改善患者的肾功能,改善临床症状,值得在临床推广。

Objective To investigate the significance of invigorating spleen and qi in patients with chronic glomerulonephritis of deficiency of spleen qi.Methods From October 2018 to January 2020 in Chengji Hospita of Shenyang Orthopedics Hospital,100 cases of patients with chronic glomerulonephritis,traditional Chinese medicine syndrome differentiation for deficiency of spleen qi,were randomly divided into experimental group and control group.The control group of 50 cases was treated with conventional treatment group.50 cases in the experimental group were given invigorating spleen and qi therapy on the basis of the control group.The renal function and TCM symptom score between the two groups was compared.Results BUN,24 h urine protein quantitative,Scr in the experimental group were better than those in the control group,and the difference was statistically significant(P<0.05).The fatigue,edema,food and less natriuretic,epigastric distension,loose stool and other integral in the experimental group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The treatment of chronic glomerulonephritis with invigorating spleen and qi can effectively improve renal function and clinical symptoms in patients with chronic glomerulonephritis,which is worthy of clinical promotion.