态靶辨证在脾虚湿瘀型慢性胃炎中的运用——黄芪建中汤加蒲公英、白及、生薏苡仁

Application of‘State-Target’Strategy in Chronic Gastritis with Spleen Deficiency,Dampness and Blood Stasis:Huangqi Jianzhong Decoction(黄芪建中汤)with Pugongying(Herba Taraxaci),Baiji(Rhizoma Bletillae)and Yiyiren(Semen Coicis)

慢性胃炎作为消化系统常见病,其发病率高、病情顽固、易反复发作,严重影响患者的生活质量,在临床上越发引起重视。仝小林院士提出"态靶因果"辨治方略诊疗疾病,分阶段与辨态势相结合,以"调态"为治疗大方向,同时"打靶",以针对疾病、症状、临床指标广覆盖、多靶点,临床疗效显著且安全。脾虚湿瘀型慢性胃炎以幽门螺旋杆菌感染为因,以胃黏膜变薄、水肿、出血(虚、湿、瘀)为果,选用黄芪建中汤为靶方,以温中健脾,和胃止痛,恢复枢机运转为大方向调态,蒲公英、白及、生薏苡仁为靶药,杀灭幽门螺旋杆菌、抑制胃酸分泌、保护胃黏膜精准专攻打靶,疗效显著。

As a common disease of the digestive system,chronic gastritis has highincidence,refractory conditionand recurrent attacks,which seriously affects the quality of life of patients,and has attracted more and more clinical attention.Professor TONG Xiaolin proposes the strategy of‘state-target-cause-prognosis’.The treatment is based on the combination of state and stage.With‘state’as the general direction of treatment,and‘target’at the same time,the strategy has wide coverage and multiple targets for diseases,symptoms and clinical indicators.Chronic gastritis with spleen deficiency,dampness and blood stasis is caused by Helicobacter pylori infection,with thinning of gastric mucosa,edemaand bleeding(deficiency,dampness,blood stasis)as the result.The target formulaHuangqi Jianzhong Decoction(黄芪建中汤)adjusts‘state’with the method of warming minor center and strengthening spleen,harmonizing stomach and relieving pain and resuming the operation of minor center cardinal.The target drugs[Pugongying(Herba Taraxaci),Baiji(Rhizoma Bletillae)and Yiyiren(Semen Coicis)]aim to precisely‘target’with the method of killing Helicobacter pylori,inhibiting gastric acid secretion and protecting the gastric mucosa.