2016—2019年广西横县华支睾吸虫病监测结果分析

Surveillance on clonorchiasis in 2016—2019 in Heng county,Guangxi

目的掌握横县华支睾吸虫病流行变化情况,为政府制定防控策略和措施提供科学依据。方法2016年、2018年、2019年在横县按东、西、南、北、中五个方位各随机选1个行政村作为监测点,按随机整群抽样方法开展华支睾吸虫感染和问卷调查。每年每个监测点选择3岁以上居民200人,采用改良加藤厚涂片法检测华支睾吸虫卵。结果2016—2019年共监测3033人,华支睾吸虫感染率为32.6%,男、女性感染率分别为42.1%和21.9%,男、女性感染率差异有统计学意义(χ^(2)=140.255,P<0.001)。2016年、2018年和2019年华支睾吸虫感染率分别为35.6%、30.5%和31.7%,不同年份感染率差异有统计学意义(χ^(2)=6.562,P=0.038)。横州镇北村居民感染率(45.5%)最高,百合镇庙庄村最低(17.5%),不同地点感染率差异有统计学意义(χ^(2)=106.648,P<0.001)。平时经常吃鱼生和不吃鱼生居民华支睾吸虫感染率分别为57.3%和21.7%,有40.0%华支睾吸虫病患者表示驱虫治疗后还会继续吃鱼生。结论横县属华支睾吸虫感染率稍有下降,但仍处于高水平,吃鱼生是当地华支睾吸虫感染的主要来源,居民对其感染危害认识不足,需强化健康教育。

Objective To determine the trend of the prevalence of clonorchiasis in Heng county and provide scientific bases for the government to make prevention and control policy of clonorchiasis.Methods In 2016,2018,and 2019,one administrative village was randomly selected as the monitoring point from the east,south,west,north,and center of Heng county.Questionnaire survey on Clonorchis sinensis infection was conducted according to random cluster sampling method.Two hundred residents aged above 3 were selected for survey from each monitoring point.Clonorchis sinensis eggs were detected by the method of the modified Kato-Katz thick.Results In total,3033 individuals were surveyed between 2016 and 2019.The total prevalence of Clonorchis sinensis infection was 32.6%.The prevalence in male and female were 42.1%and 21.9%,respectively.The difference in the prevalence between male and female was significant(χ^(2)=140.255,P<0.001).The prevalence of Clonorchis sinensis infection in 2016,2018,and 2019 were 35.6%,30.5%,and 31.7%,respectively.The differences in infection rates in different years were statistically significant(χ^(2)=6.562,P=0.038).The prevalence of Clonorchis sinensis infection in Bei village,Hengzhou town,was the highest(45.5%)while Miaozhuang village,Baihe town was the lowest(17.5%).The difference between the two villages was significant(χ^(2)=106.648,P<0.001).The prevalence of Clonorchis sinensis in eating and non-eating raw fish groups were 57.3%and 21.7%,respectively.More than 40%of subjects with Clonorchiasis expressed that they would continue to eat raw fish after deworming therapy.Conclusion The infection rate of Clonorchis sinensis in Heng County decreased slightiy,but it was still at a high level.Eating raw fish is the major infection source of Clonorchis sinensis infection.Residents are not fully aware of the harm of the infection.Health education should be enhanced.