^(18)F-FDG/PET-CT与^(99m)Tc-MDP骨显像在诊断肿瘤骨转移的临床价值分析

Clinical Value of ^(18)F-FDG/PET-CT and ^(99m)Tc-MDP Bone Imaging in the Diagnosis of Tumor Bone Metastasis

目的18氟代脱氧葡萄糖的正电子发射计算机断层扫描显像(18F-FDG/PET-CT)与99锝代亚甲基二膦酸盐(99mTc-MDP)骨显像在诊断肿瘤骨转移的临床价值分析。方法选择2016年1月至2018年1月到我院就诊恶性肿瘤患者110例,其中发生骨转移患者63例,未发生骨转移患者47例,所有患者均进行18F-FDG/PET-CT与99mTc-MDP骨显像检测。统计两种检测方式的诊断效能、对不同部位骨转移病灶检出率、对不同类型肿瘤骨转移的检出率。结果18F-FDG/PET-CT检测诊断准确性、灵敏性均高于99mTc-MDP骨显像(P<0.05);18F-FDG/PET-CT检测对胸部、脊柱的骨转移病灶检出率高于99mTc-MDP骨显像(P<0.05);18F-FDG/PET-CT对溶骨性骨转移病灶检出率高于99mTc-MDP骨显像(P<0.05)。结论18F-FDG/PET-CT检测肿瘤骨转移诊断效能更高。

Objective To a nalyze the clinical value of 18F-2-fluoro-2-deoxy-D-glucose/positron emission tomogra phycomputed tomography(18F-FDG/PET-CT)and 99 mTc-methylene-diphosphonic acid(99mTc-MDP)bone imaging in the diagnosis of tumor bone metastasis.Methods A total of 110 patients with malignant tumors treated in the hospital from January 2016 to January 2018 we re selected,including 63 patients with bone metastases and 47 patients without bone metastases.All patients were given 18F-FDG/PET-CT and 99mTc-MDP bone imaging detection.The diagnostic efficacy of the two detection methods was counted,and the detection rates of bone metastases at different sites were counted in the two detection methods,and the detection rates of different types of tumor bone metastasis were counted in the two detection methods.Results The diagnostic accuracy and sensitivity of 18F-FDG/PET-CT were higher than those of 99mTc-MDP bone imaging(P<0.05).The detection rates of bone metastases in the chest and spine detected by 18F-FDG/PET-CT were higher than those by 99mTc-MDP bone imaging(P<0.05).The detection rate of osteolytic bone metastasis by 18F-FDG/PET-CT was higher than that by 99mTc-MDP bone imaging(P<0.05).Condusions 18F-FDG/PET-CT has high diagnostic efficacy in the diagnosis of tumor bone metastasis.