幽门螺杆菌与房颤关系的研究进展

Advances of research in relationship between Helicobacter pylori and atrial fibrillation

幽门螺杆菌是一种存在于人体胃腔黏膜的革兰氏阴性细菌,对人体有着不可忽视的危害;而房颤是最常见的持续性心律失常,患病率和致死致残率高。新近多项研究表明幽门螺杆菌与房颤密切相关。本文综述幽门螺杆菌导致房颤的可能机制、房颤流行病学、幽门螺杆菌相关指标对房颤相关治疗和预后的预测价值的研究进展。

As a gram-negative bacterium that exists in the human gastric mucosa,Helicobacter pylori has a nonnegligible harm to the human body.Atrial fibrillation,as the most common persistent arrhythmia,has a high morbidity,mortality and disability.Several recent studies have shown that Helicobacter pylori is closely related to atrial fibrillation.This paper reviews on the possible pathogenesis of atrial fibrillation caused by Helicobacter pylori,epidemiology of atrial fibrillation,and the predictive value of Helicobacter pylori related indexes on the treatment and prognosis of atrial fibrillation.