1例获得性免疫缺陷综合征相关性脑血管炎的报道

A case report of acquired immunodeficiency syndrome-associated cerebrovascular inflammation

获得性免疫缺陷综合征(AIDS)是以全身性严重免疫缺陷为主要特征的致命性传染病,可累及消化、心血管和神经等系统等,亦可引起脑血管壁出现纤维素样坏死、炎性细胞浸润以及管腔内血栓形成等血管炎性改变,导致脑组织出现梗死或出血。其临床症状无明显特异性,且与原发性中枢神经系统血管炎(PACNS)极其相似,极易误诊误治。本文就1例肢体无力查因入院患者,诊断为AIDS相关性脑血管炎病例,详细介绍患者的临床症状和诊疗过程。随着我国艾滋病病毒(HIV)感染人数的逐年增加,AIDS相关性脑梗死的患病率也会逐年增多。相关专业医生应该注意此类疾病可能,避免误诊、误治。

Acquired immunodeficiency syndrome(AIDS),a kind of fatal infectious disease,is characterized by severe systemic immune deficiency,which may be involved gastrointestinal,cardiovascular and nervous systems,and so on.AIDS can also cause vasculitis-like changes,such as fibrinoid necrosis,inflammatory cells infiltration and thrombosis in the vascular vessels,and can lead to cerebral infarction or hemorrhage.Nonspecific clinical symptoms,which are similar to those of primary angiitis of the central nervous system(PACNS),lead to be misdiagnosed and mistreated.In this paper,a case with limb weakness of the AIDS-related cerebral vasculitis was confirmed,and the clinical symptoms and treatment process were introduced in detail.With the increasing number of human inmunodeficency virus(HIV)infections in China,the prevalence of AIDS-related cerebral infarction will increase year by year.Relevant professional doctors should pay attention to the possibility of such diseases to avoid misdiagnosis and mistreatment.