阻塞性睡眠呼吸暂停低通气综合征患者临床症状与体力活动水平的关联性分析

Correlation Between Clinical Symptoms and Physical Activity in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

研究目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)临床症状与体力活动(PA)水平间的关联性。方法:以临汾市人民医院2018年10月至2019年10月经睡眠呼吸监测(PSG)诊断为OSAHS的113例患者为研究对象,采用国际体力活动问卷(IPAQ—LF)调查PA水平,对患者在夜间进行持续7h以上的多导睡眠呼吸监测,分析患者PA水平与多导睡眠呼吸监测结果、OSAHS病情程度以及嗜睡程度的关联性。结果:(1)AHI、鼾声指数与总体力活动量呈显著负相关(P<0.01),LSaO_(2)与总体力活动量呈显著正相关(P<0.05)。其中AHI、LSaO_(2)和鼾声指数与大强度体力活动量均没有相关性(P>0.05);AHI和鼾声指数与中强度活动量有显著性负相关(P<0.01),LSaO_(2)与中强度体力活动量呈显著正相关(P<0.01);LSaO_(2)与小强度体力活动量无相关性(P>0.05),而AHI和鼾声指数与小强度体力活动量有显著负相关(P<0.05)。(2)OSAHS病情程度与总体力活动量呈显著负相关(P<0.01)。其中OSAHS病情程度与小强度体力活动量呈显著负相关(P<0.05),与中强度体力活动量存在显著负相关(P<0.01),与大强度体力活动量不存在相关性(P>0.05)。(3)嗜睡程度同小强度和大强度体力活动量不存在相关性(P>0.05),与中强度体力活动量和总体力活动量呈显著相关性(P<0.01)。结论:本研究患者AHI、LSaO_(2)、鼾声指数、OSAHS病情程度和嗜睡程度五个临床症状指标与体力活动均存在显著相关性,说明PA不足可加重OSAHS患者临床相关症状,可增加OSAHS的发病风险。小强度和中强度体力活动可以降低AHI、鼾声指数与OSAHS病情程度,中强度体力活动能减轻患者嗜睡程度并增加LSaO_(2),而大强度体力活动与OSAHS临床相关指标均无相关性。

The study aims to investigate the correlation between clinical symptoms and physical activity(PA)level in patients with obstructive sleep apnea hypopnea syndrome(OSAHS).113 patients with OSAHS diagnosed by PSG in Linfen Peoples Hospital from October 2018 to October 2019 were selected as the research objects.The PA level was investigated by international physical activity questionnaire(IPAQ-LF).It is found,firstly,AHI and snoring index were negatively correlated with total physical activity(P<0.01),while LSaO_(2) was positively correlated with total physical activity(P<0.05),among which,AHI,LSaO_(2) and snoring index had no correlation with high intensity physical activity(P>0.05);AHI and snoring index had significantly negative correlation with medium intensity physical activity(P<0.01),and LSaO_(2) had significantly positive correlation with medium intensity physical activity(P<0.01);LSaO_(2) had no correlation with low intensity physical activity(P>0.05),while AHI and snoring index had significantly negative correlation with low intensity physical activity(P<0.05).Besides,the severity of OSAHS was significantly negatively correlated with total physical activity(P<0.01).Secondly,the severity of SOAHS regatively correlated with the total physical autivity(P<0.01),among which the severity of OSAHS was significantly negatively correlated with the amount of low intensity physical activity(P<0.05),significantly negatively correlated with the amount of medium intensity physical activity(P<0.01),and not correlated with the amount of high intensity physical activity(P>0.05).lastly,there was no correlation between somnolence degree and low and high intensity physical activity(P>0.05),but significant correlation between somnolence degree and medium intensity physical activity and total physical activity(P<0.01).It is concluded that AHI,LSaO_(2),snoring index,severity of OSAHS and somnolence degree are significantly correlated with physical activity,indicating that PA deficiency can aggravate the clinical symptoms of patients with OSAHS and increase the risk of OSAHS.Low intensity and medium intensity physical activity can reduce AHI,snoring index and the severity of OSAHS,medium intensity physical activity can reduce somnolence degree and increase LSaO_(2),while high intensity physical activity has no correlation with clinical indicators of OSAHS.