CDDS超纯水血液透析与普通透析对维持性血透患者在营养状况方面的影响对比

Comparison of the effects of CDDS ultrapure water hemodialysis and ordinary dialysis on the nutritional status of patients with maintenance hemodialysis

目的探讨中央供透析液系统(CDDS)模式与传统透析模式对维持性血液透析患者营养状况方面的不同影响。方法以本中心透龄>6个月的患者为研究对象,采用随机方法将患者分为CDDS实验组和传统透析对照组。实验组的透析液供给采用CDDS模式,对照组的透析液供给采用非中央供液模式。在透析期间给予统一饮食,并拟定透析间期饮食食谱。运用主观全面营养评价法(SGA)评测两组患者基础营养饮食状况。记录两组患者自2017年10月开始的实验室检查:白蛋白(Alb),血红蛋白(Hb),C反应蛋白(CRP)。结果经过6个月的观察,发现实验组CRP降低水平显著高于对照组(P<0.05),Alb、Hb的升高水平显著高于对照组(P<0.05)。结论维持性透析患者应用CDDS超纯透析液可以在一定程度上改善患者营养状况。

Objective To compare the effects of central dialysate delivers system(CDDS)ultrapure water hemodialysis and ordinary hemodialysis on nutritional status of maintenance hemodialysis patients.Methods Patients with dialysis age greater than 6 months in the center were selected as the research object,and the patients were randomly divided into CDDS experimental group and traditional dialysis control group.Dialysate in the experimental group was supplied in CDDS mode,while dialysate in the control group was supplied in non-central mode.During dialysis,the patients were given a unified diet,and the diet for the interdialysis period was formulated.Subjective global assessment(SGA)was used to assess the basic nutritional status of the two groups.Laboratory examinations of albumin(ALB),hemoglobin(Hb)and C-reactive protein(CRP)were recorded in both groups since October,2017.Results After 6 months of observation,CRP reduction in the experimental group was significantly higher than that in the control group(P<0.05).The elevated level of ALB and HB was significantly higher than that of control group(P<0.05).Conclusions CDDS ultrapure dialysate can improve nutritional status of maintenance dialysis patients to a certain extent.