生物医用镁合金材料的应用及耐蚀性研究进展

Research Progress of Application and Corrosion Resistance of Medical Magnesium Alloy Materials

镁合金具有良好的力学性能,与人体生物相容性好,尤其是在人体内具有可生物降解的特点,是一种非常有前途的可降解生物医用金属材料。综述了镁和镁合金作为可降解生物医用材料的优越性和存在问题,生物医用镁合金的国内外研究现状,镁和镁合金的腐蚀机理及腐蚀类型,总结了当前用于提高生物医用纯镁和镁合金耐蚀性的方法,并对生物医用镁合金体内体外耐蚀性能进行了比较,展望了可降解生物医用材料的未来发展前景和研究方向。

Magnesium alloys have good mechanical properties and good biocompatibility with humans. Especially,magnesium alloys possess the characteristics of biodegradable in the human body,which endows them as a kind of very promising biodegradable biomedical metal materials.In this work,the advantages and problems of magnesium and magnesium alloys as biodegradable biomedical materials was summarized,as well as the research status of magnesium alloys for biomedical applications at home and abroad. In addition,the corrosion mechanism and types of magnesium and magnesium alloys and the current methods for improving the corrosion resistance of pure magnesium and magnesium alloys for biomedical applications were introduce. The corrosion resistance of biomedical magnesium alloys in vitro and in vivo was compared,and the future development prospects and research directions of biodegradable biomedical materials were predicted.