多囊卵巢综合征的中西医研究现状

The Current Situation of Chinese and Western Medicine Research on Polycystic Ovarian Syndrome

多囊卵巢综合征(polycystic ovary syndrome,PCOS)作为代谢性疾病,其病因病机较为复杂,至今仍无法明确。西医认为,其发生发展主要与胰岛素抵抗、高雄激素血症及慢性炎症密切相关;中医学则认为,其发生发展主要是因肾、肝、脾三脏及冲任二脉功能失调所致。西医治疗PCOS主要是采用胰岛素增敏剂、避孕药等药物,生活方式干预及手术治疗为主,虽然见效较快,但存在不良反应较大、术后附件易粘连等弊端;中医治疗则选用针灸、穴位埋线、药物调理等以滋补肝肾、健脾除湿、调理冲任。今后,应多进行动物实验以探究多囊卵巢综合征伴慢性炎症的发病机制,并验证中药、针灸治疗PCOS的疗效。

Polycystic ovary syndrome(PCOS)is a metabolic disease.Its etiology and pathogenesis are complex,and still unclear until today.Western medicine believes that its occurrence and development are closely related to insulin resistance,hyperandrogenemia and chronic inflammation;while TCM believes that its occurrence and development are mainly due to the dysfunction of kidney,liver,spleen,TV and CV.Western medicine treatment of PCOS mainly uses insulin sensitizer,contraceptives and other drugs,lifestyle intervention and surgical treatment,although the effect is fast,but there are many disadvantages,such as large adverse reactions,postoperative attachment adhesion.While in TCM,acupuncture and moxibustion,catgut embedment in acupoint,and drug conditioning are used to nourish the liver and kidney,invigorate the spleen and remove dampness,and regulate TV and CV.In the future,more animal experiments should be carried out to explore the pathogenesis of PCOS with chronic inflammation,and to verify the efficacy of Chinese medicinala and acupuncture and moxibustion on PCOS.