摘要
Dear Editor,The COVID-19 pandemic has covered more than 200 countries and regions around the world since its outbreak in January 2020.To date,the SARS-CoV-2 virus has caused>1.2 million deaths.The mortality rate of COVID-19 is closely concerned with the clinical symptoms of the patients from mild-to-severe disease.Notably,in its most severe form,COVID-19 leads to life-threatening pneumonia and acute respiratory distress syndrome(ARDS),which is mostly accom-panied by a hyperactive immune response called"cytokine storm"and has high death rates from 40 to 50%.
基金
This work was supported by the National Key Research and Development Program of China(No.2016YFA0201402)
National Natural Science Foundation Regional Innovation and Development(U19A2003)
the National Major Scientific and Technological Special Project for"Significant New Drugs Development"(No.2018ZX09733001).
