平均血小板体积与急性冠状动脉综合征的研究进展

Research progress of mean platelet volume and acute coronary syndrome

血小板在止血和血栓形成中发挥显著作用,活化的血小板通过释放参与炎症、动脉粥样硬化和血栓形成的介质,在心血管疾病的发病机制中发挥重要作用。平均血小板体积是血小板大小和活性的指标。大血小板的代谢和酶促活性更强,具有更强的促炎和血栓形成潜力,与急性冠状动脉综合征的发生发展密切相关。

Platelets are actively involved in hemostasis and thrombosis.Activated platelets play an important role in the pathogenesis of cardiovascular disease by releasing many mediators involved in inflammation,atherosclerosis and thrombosis.Mean platelet volume is accepted as an indicator of platelet size and platelet activation.Large platelets are metabolically and enzymatically more active,which have a higher tendency to enhance inflammatory processes and thrombotic risk and are closely related to the occurrence and development of acute coronary syndrome.