老年根治性膀胱切除术患者衰弱评估及安全管理的研究进展

Research progress on frailty assessment and safety management of aged patients undergoing radical cystectomy

衰弱是指由于个人脆弱性增加及保持自我内在平衡能力下降而出现的临床综合征,与老年膀胱癌疾病的发展密切相关。癌症加速机体衰弱的发生,而术前衰弱作为根治性膀胱切除术患者不良健康结局的独立预测因素,在老年根治性膀胱切除术患者围手术期安全管理方案的制订中有重要指导意义。目前,我国对老年根治性膀胱切除术患者衰弱的研究尚处于起步阶段。本文对术前衰弱评估、膀胱癌与衰弱的关系、老年根治性膀胱切除术衰弱患者安全管理策略等进行综述,以期为国内老年膀胱癌患者衰弱研究的发展提供借鉴。

Frailty refers to a clinical syndrome that occurs due to an increase in personal vulnerability and a decline in the ability to maintain one's internal balance,which is closely related to the development of bladder cancer in the aged.Cancer accelerates frailty,and preoperative frailty is an independent predictor of adverse health outcomes for patients undergoing radical cystectomy.It is of great significance in guiding the formulation of perioperative safety management plans for aged patients undergoing radical cystectomy.At present,China's research on the frailty of aged patients undergoing radical cystectomy is still in its infancy.This article reviewed the preoperative frailty assessment,the relationship between bladder cancer and frailty,and the safety management strategies for frail aged patients undergoing radical cystectomy,in order to provide a reference for the development of preoperative frailty research in aged patients with bladder cancer in China.