TALE靶标基因与农作物广谱持久抗病育种

TALE Targets for Durable Broad-Spectrum Resistance Breeding in Crops

为了揭示黄单胞菌与植物间互作的遗传学基础,培育广谱持久抗病的农作物,本文对这一领域重要研究进展进行了综述.首先指出了黄单胞菌引起植物病害的严重性,分析了黄单胞菌与植物互作如何导致植物抗病或感病,归纳了TALE蛋白主要作用植物的靶标类型,分析了植物基础转录因子TFIIA与NLR类R基因在植物抗病性中的重要性,认为基因编辑TALE蛋白的效应子结合元件(EBE)是未来作物广谱持久抗病育种的重要方向.

To reveal the genetic basis of the interaction between Xanthomonas pathogens and their host plants for breeding durable broad-spectrum resistance crops,the recent important progress in these fields are summarized.The devastation of plant diseases caused by Xanthomonas species is determined by Xanthomonas T3 SS effectors,mainly transcription activator-like effectors(TALEs),which target effector-binding element(EBE)sites of either crop resistance(R)or susceptibility(S)genes.Then,the five types of TALE-targets in plants are briefly stated and the importance of plant general transcription factors TFIIA in the activation of NLR-type R genes in plant resistance is stressed.Finally,that gene-editing of EBEs of R or S genes is proposed to be the new strategy for resistance breeding to control crop diseases in the future.