非抑制离子色谱法测定多种状态进出口化妆品中三乙醇胺的含量

Determination of Triethanolamine in Cosmetics under Multiple States by Non-suppressed Ion Chromatography

本文采用离子色谱-电导检测器建立了测定多种状态进出口化妆品中三乙醇胺含量的检测方法。方法对流动相、萃取时间等进行了优化,优选2.5 mmol/L甲烷磺酸-5%乙腈水溶液为流动相,采用正己烷旋涡提取10 min。试验结果表明,方法在1 mg/L500 mg/L浓度范围线性良好,相关系数为0.9999,方法的检出限和定量限分别为30 mg/kg和80 mg/kg,水状、膏状、乳状、粉状、油状化妆品低、中、高三水平回收率为94%113%,对应的精密度RSD为3.32%4.92%,证明该方法满足实际检测需要,将该方法用于市售进出口化妆品样品中三乙醇胺的测定,结果部分有检出,说明风险存在。

The method of using conductance detector,an ion chromatogram instrument,was applied in the determination of the content of triethanolamine in import and export cosmetics under multiple states.The conditions of mobile phase and the extractant as well as the extraction time were optimized in the experiments.By vortex extraction with n-hexane for 10 minutes,2.5 mmol/L methanesulfonic and acid-5%acetonitrile aqueous solution was selected as the mobile phase.The results showed that the standard curve had good linearity in the range of 1 mg/L 500 mg/L with correlation coefficient of 0.9999.The limit of detection(LOD)and quantitation(LOQ)of the method were 30 mg/kg and 80 mg/kg,respectively.The recoveries were at the range of 94%113%at low,medium and high concentration levels for aqueous,pasty,cream,solid states of cosmetics.And the relative standard deviation was 3.32%4.92%.The method was proved to be satisfactory in the actual tests.And when such method was applied in determination of triethanolamine in cosmetics on sale in the market,positive result was obtained,demonstrating that risks existed.