中空介孔二氧化硅在生物医学领域中的应用研究进展

The Research Progress in the Application of Hollow Mesoporous Silica in the Field of Biomedicine

中空介孔二氧化硅具有中空腔结构、低密度、大比表面积、良好的生物相容性和稳定性以及表面易修饰等理化特性,在生物医学领域中受到广泛关注.该文主要概括了近年来功能化中空介孔二氧化硅在药物控释、靶向和生物成像中的应用研究进展,同时对目前中空介孔二氧化硅在临床应用中面临的问题进行了分析.

Hollow mesoporous silica has a hollow cavity structure,low density,large specific surface area,good biocompatibility and stability,easy surface modification and other physical and chemical properties,and has attracted wide attention in the biomedical field.The research progress of functionalized hollow mesoporous silica in drug controlled release,targeting and bioimaging applications in recent years is mainly summarized,and the current problems of hollow mesoporous silica in clinical applications are analyzed.