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非酒精性脂肪性肝病的流行现状 被引量:10

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摘要 非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是遗传易感和胰岛素抵抗引起的代谢功能障碍相关脂肪性肝病,肝脏特征性病变包括大泡性肝细胞脂肪变、小叶内炎症、肝细胞气球样变以及肝纤维化[1]。随着全球前所未有的工业化进程以及人类生活方式的巨大变化,21世纪以来NAFLD患病率呈逐年上升趋势,现已成为全球第一大慢性肝病。考虑到始于儿童期的肥胖的持续流行、2型糖尿病患病率的不断攀升以及人口老龄化等因素的影响,预计NAFLD的患病率以及进展期肝病患者的比例将继续增加。
出处 《肝脏》 2021年第1期87-88,共2页 Chinese Hepatology
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