早产儿支气管肺发育不良发生率和危险因素探讨

Discussion on the Incidence and Risk Factors of Bronchopulmonary Dysplasia in Premature Infants

目的探讨早产儿支气管肺发育不良(BPD)发生率和危险因素。方法回顾性分析752例小胎龄早产儿的临床资料,分为BPD组和非BPD组,分析早产儿支气管肺发育不良的危险因素。结果小胎龄早产儿的BPD发生率为13.83%。多因素Logistic回归分析显示,宫内感染史、吸入氧气浓度>40%、出生2周内输注红细胞、胎膜早破是早产儿BPD发生的危险因素(P<0.05)。结论小胎龄早产儿BPD的危险因素较多,临床应重视早产儿BPD的防治,制定针对性防治策略。

Objective To explore the incidence and risk factors of bronchopulmonary dysplasia(BPD)in premature infants.Methods The clinical data of 752 premature infants with shorter gestational age were retrospectively analyzed,and divided into BPD group and non-BPD group.The risk factors of BPD in premature infants were analyzed.Results The incidence of BPD in premature infants with shorter gestational age was 13.83%.Multivariate Logistic regression analysis showed that the history of intrauterine infection,inhaled oxygen concentration>40%,transfusion of red blood cells within 2 weeks of birth,premature rupture of membranes were the risk factors for occurrence of BPD in premature infants(P<0.05).Conclusions There are many risk factors for BPD in premature infants with shorter gestational age.Therefore,clinical attention should be paid to the prevention and treatment of BPD in premature infants,and targeted prevention and treatment strategies should be developed.