参苓白术散联合穴位埋线治疗单纯性肥胖的疗效观察

An Observation of the Effect of Shenlingbaizhu Powder Combined with Acupoint Catgut Implantation in Treating Simple Obesity

目的:探讨参苓白术散联合穴位埋线治疗单纯性肥胖患者的临床疗效。方法:将2017年6月至2020年3月我院收治的单纯性肥胖患者128例,随机分为对照组和治疗组,每组64例。对照组给予常规治疗,治疗组在对照组的基础上加用参苓白术散煎服联合穴位埋线治疗,疗程为3个月。比较两组的临床疗效,治疗前后体重、体重指数(BMI)、腰围、腰臀比(WHR)、腰围身高比(WHtR)、体脂率(F%)、空腹血糖(FBG)、空腹胰岛素(FINS)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-2(IL-2)水平,并计算胰岛素抵抗指数(HOMA-IR)。结果:治疗后,治疗组的总有效率显著高于对照组(P<0.05);治疗后,两组的中医证候积分、体重、BMI、腰围、WHR、WHtR、F%均较治疗前降低(P<0.05),且治疗组低于对照组(P<0.05);治疗后,两组血清FBG、FINS、TC、TG、LDL-C、TNF-α、IL-2、HOMA-IR水平均较治疗前降低(P<0.05),且治疗组均低于对照组(P<0.05);治疗后,两组血清IL-6、HDL-C水平均较治疗前升高(P<0.05),且治疗组均高于对照组(P<0.05)。结论:参苓白术散煎服联合穴位埋线疗法可以降低单纯性肥胖患者体重,改善胰岛素抵抗,抑制炎症微状态。

Objective:To observe the clinical efficacy of Shenlingbaizhu powder combined with acupoint catgut implantation in the treatment of simple obesity patients.Methods:128 patients with simple obesity admitted to our hospital from June 2017 to March 2020 were randomly divided into a control group and a treatment group,with 64 cases in each group.The control group was given conventional treatment,and the treatment group was given Shenlingbaizhu powder decoction combined with acupoint implantation treatment on the basis of the control group.The course of treatment was 3 months.The clinical efficacy of the two groups before and after treatment were compared,as well as body weight,body mass index(BMI),waist circumference,waist to hip ratio(WHR),waist circumference to height ratio(WHtR),body fat rate(F%),fasting blood glucose(FBG),fasting insulin(FINS),total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),white blood cells Interleukin-2(IL-2)levels,and calculate the insulin resistance index(HOMA-IR).Results:After treatment,the total effective rate of the treatment group was significantly higher than that of the control group(P<0.05);after treatment,the scores of TCM syndromes,weight,BMI,waist circumference,WHR,WHtR,and F%of the two groups were lower than before treatment(P<0.05),and the scores of the treatment group are lower than those of the control group(P<0.05).After treatment,serum FBG,FINS,TC,TG,LDL-C,TNF-,IL-2,HOMA-IR levels were lower than before treatment in both groups(P<0.05),and the treatment group had lower records than the control group(P<0.05).After treatment,serum IL-6 and HDL-C levels in both groups were higher than before treatment(P<0.05),and the treatment group had higher records than the control group(P<0.05).Conclusion:Shenlingbaizhu powder decoction combined with acupoint catgut implantation therapy could reduce the weight of simple obese patients,improve insulin resistance,and inhibit inflammation.