摘要
人脑组织库是通过对捐献的脑组织进行采集、保存、研究、分享,从而服务于神经病学和神经科学发展的一个机构。在接受捐献的遗体组织过程中,为了避免感染潜在的传染性疾病的风险,需要提出生物安全管理的具体操作方案和操作标准。在处理遗体组织样本时,若能及时了解潜在的生物安全风险,符合相应等级的生物安全防护要求,掌握相关的生物安全防护知识,建立起相关的生物安全制度与体系,对于人脑组织库相关人员的安全及人脑组织库的平稳安全运行都至关重要。作者在查阅、学习、借鉴相关实验室生物安全防护及个人安全防护文件及标准的基础上,总结并撰写了相应于人脑组织库的生物安全防护标准及流程,拟作为中国人脑组织库建设的生物安全操作依据。
The human brain tissue bank is an institution dedicated to the development of neurology and neuroscience through collection,preservation,research and sharing of donated human brain tissues.In order to maintain environment and staff personal safety,it is necessary to establish standard operation procedure for prevention of potential contagious diseases.During autopsy or brain only autopsy,it is necessary to evaluate the biological safety grades beforehand,prepare for potential risks,adhere to the requirement of corresponding levels of biological safety,and establish biological safety system.Following standard biosafety procedure is vital for human brain and tissue banking.On the basis of consultation,literary and regulation searches,and our own experiences,this paper summarizes the biosafety standards and procedures for human brain and tissue banking as guidelines during practice.
作者
尹金辉
黄越
卞修武
陈彪
陈生弟
崔慧先
董格红
郭慧君
何跃颂
朴月善
唐北沙
王德田
吴安华
张玉琪
周韧
张力伟
YIN Jin-hui;HUANG Yue;BIAN Xiu-wu;CHEN Biao;CHEN Sheng-di;CUI Hui-xian;DONG Ge-hong;GUO Hui-jun;HE Yue-song;PIAO Yue-shan;TANG Bei-sha;WANG De-tian;WU An-hua;ZHANG Yu-qi;ZHOU Ren;ZHANG Li-wei(Beijing Tiantan Hospital,Capital Medical University,China National Clinical Research Center for Neurological Diseases,Beijing100071,China;Beijing Tiantan Hospital,Capital Medical University,Pathology Department,Beijing100071,China;The First Affiliated Hospital of Army Medical University,Chongqing 400038,China;Xuanwu Hospital of Capital Medical University,China National Clinical Medical Research Center for Geriatric Diseases,,Beijing 100053,China;Xuanwu Hospital of Capital Medical University,Pathology Department,Beijing 100053,China;Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China;Hebei Medical University,Shijiazhuang,Hebei 050017,China;Pathological Equipment Branch of Chinese Medical Equipment Association,Beijing 100089,China;Beijing Source of Judicial Identification Center of Science Evidence,Beijing 100062,China;China National Clinical Research Center of Geriatrics,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China;Department of Pathology,Peking Union Medical College Hospital,Beijing 100730,China;The Frist Hospital of China Medical University,Shenyang,Liaoning 110001,China;Yuquan Hospital of Tsinghua University,Beijing 100040,China;Brain Bank of Zhejiang University,Hangzhou,Zhejiang 310058,China)
出处
《阿尔茨海默病及相关病杂志》
2021年第1期13-20,共8页
Chinese Journal of Alzheimer's Disease and Related Disorders
关键词
人脑组织库
生物安全
生物危害
生物安全等级
个人防护装备
Brain tissue bank
Biosafety
Biohazard
Biological safety level
Personal protective equipment
